PRACTICE AREA OVERVIEW
Dr. Harding prepares and prosecutes U.S., foreign, and international patent applications, as well as advises clients with regard to patent-related administrative proceedings, including interferences, European third-party document submissions, and European oppositions. She also prepares legal opinions, such as patentability, inventorship, freedom to use, and infringement/non-infringement opinions. License drafting and interpretation and client counseling regarding portfolio management and portfolio acquisition/transfer are additional aspects of Dr. Harding’s work.
Dr. Harding’s technology areas include molecular and cell biology, basic and applied plant biology and genetics, biofuel production, cancer and immunology, infectious diseases (including viral diseases), vaccines, and microarray (including nucleic acid and protein arrays) and high throughput technologies. Her laboratory experience includes recombinant DNA techniques, protein isolation and analysis, immunology, and molecular, plant, and microbial genetics, as well as plant tissue culture (monocots and dicots). Research systems in which Dr. Harding has worked include tobacco, tomato, barley, wheat, and cucumber, as well as bacteria, yeast (S. cerevisiae), and Chlamydomonas.
PRIOR PROFESSIONAL EXPERIENCE
U.S. District Court – Northern District of N.Y., Hon. Thomas J. McAvoy, Chief Judge, Binghamton, NY
Judicial Externship | Spring 1998
Cornell University Law School, Ithaca, NY
Research Assistant to Professor Yvonne Cripps | Fall 1997
Sterne, Kessler, Goldstein & Fox P.L.L.C., Washington, D.C.
Summer Associate | May 1997 – August 1997
University of California, Davis, CA
Teaching Assistant, Department of Microbiology | Spring 1995
Graduate Research Associate, Depts. of Microbiology and Plant Biology | May 1991 – June 1996
- Member, Oregon Patent Law Association
- Inhibitor of DNA Methylation (WO 03/012051 A2)
- Measurements of Multiple Molecules Using a Cryoarray (6,951,761)
- Method of Detecting Ivermectin Sensitivity in a Canine Subject by Identifying a Mutation in a MDR1-Encoding Sequence (6,790,621)
- Phenylthiocarbamide (PTC) Taste Receptor (7,314,725)
- Oxidation-Reduction Sensitive Green Fluorescent Protein Variants (7,314,736)
- Method to Trigger RNA Interference (8,030,473)
- Platelet Derived Growth Factor Receptor Alpha (PDGFRA) Polypeptides Comprising Activating Mutation(s) (8,202,969)
- Prevention of Tissue Ischemia, Related Methods and Compositions (8,236,313)
- Closterovirus Vectors and Methods (8,415,147)
- LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis (8,535,884)
- Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis (8,828,356)
- Multi-Domain Amphipathic Helical Peptides and Methods of Their Use (8,835,378)
PRESENTATIONS AND PUBLICATIONS
- Harding, T.M., Morano, K.A., Scott, S.V. and Klionsky, D.J. (1995). Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J. Cell Biol., 313:591-602.
- Kim, J., Alizadeh, P., Harding, T.M., Hefner-Gravink, A., and Klionsky, D.J. (1996) Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: Potential commercial applications. Appl. Environ. Microbiol., 62:1563-1569.
- Harding, T.M., Hefner-Gravink, A., Thumm, M., and Klionsky, D.J. (1996) Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway. J. Biol. Chem., 271:17621-17624.
- Wang, Y.-X., Xhao, H., Harding, T.M., Gomes de Mesquita, D.S., Woldringh, C.L., Klionsky, D.J., Munn, A.L., and Weisman, L.S. (1996) Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Mol. Biol. Cell, 7:1375-1389.